Scotland coach Gregor Townsend has named Finn Russell in his group to face England after the fly-half missed the Autumn Nations Cup by damage.
Full-back Stuart Hogg will lead the facet with Cameron Redpath making his debut for the nationwide facet.
“We learned a lot about ourselves and where the game is going during our Autumn campaign, and we aim to build on this base during the next seven weeks,” Towsend mentioned in a press release.
“It’s always a pleasure to welcome a new player into our squad and we are looking forward to Cam Redpath winning his first cap on Saturday. We have been really impressed with Cam’s contributions in the time he has been with us in camp.
“There are a variety of skilled gamers within the backline to assist make his transition to Test rugby go as easily as doable, and he has the mindset and skillset to thrive at this stage.”
Wingers Sean Maitland and Duhan van der Merwe are part of five changes to the side that faced Wales in the postponed Six Nations in October.
Matt Ferguson starts at No. 8 while another debut is handed to hooker George Turner.
— Scottish Rugby (@Scotlandteam) February 4, 2021
Rory Sutherland and Zander Ferguson make up the front-row with Turner.
Ali Price companions Russell and Chris Harris is paired with Redpath.
Scott Cummings and Jonny Gray function at second row, with Hamish Watson and Jamie Ritchie finishing the pack.
The Calcutta Cup recreation marks 150 years because the two sides first met and Scotland will commemorate the event with a reputation from the 1871 group embroidered on every jersey.
Stuart Hogg (captain), Sean Maitland, Chris Harris, Cameron Redpath, Duhan van der Merwe, Finn Russell, Ali Price, Rory Sutherland, George Turner, Zander Fagerson, Scott Cummings, Jonny Gray, Jamie Ritchie, Hamish Watson, Matt Fagerson.
Replacements: David Cherry, Oli Kebble, WP Nel, Richie Gray, Gary Graham, Scott Steele, Jaco van der Walt, Huw Jones.